Poster Session 2 — ASN Events

Poster Session 2 — ASN Events

Poster Session 2

Searching for therapeutic targets from whole transcriptome of oral cancer (#200)

Overlapping promoters and operators of Mycobacteriophage D29 ―An insight into the evolution of regulatory elements (#201)

Niketa Bhawsinghka

Molecular Characterisation of Cell Type-Specific Routes to Pluripotency (#202)

Fernando J Rossello

Supervised learning methods for distinction of cattle production type (#204)

Veronika Kukučková

Understanding the expression of human disease genes using FANTOM5 expression profiles. (#205)

An atlas of human long non-coding RNAs reveals their heterogeneity and evidence of their widespread function (#206)

Elucidating novel mechanisms for growth control and cancer progression: linking RAS and PI3K pathways with MYC transcription via FUBP1 (#207)

Identification of a Distal Regulatory Element of the Human Neuroglobin Gene (#208)

Gene Prioritization in Novel Copy Number Variants Regions Associated with Autism (#209)

Hamid Alinejad-Rokny

THE -115 SITE OF THE GAMMA-GLOBIN PROMOTER IS A CRITICAL CIS-ACTING ELEMENT INVOLVED IN BINDING A GAMMA-GLOBIN REPRESSOR (#210)

Gabriella E Martyn

Cryo-EM of human telomerase (#211)

A novel high affinity, specific inhibitor of the histone acetyltransferases KAT6A (MOZ) and KAT6B (QKF). (#212)

Rapid transgenerational adaptation of a reef fish to climate change (#213)

Implication of p400 ATPase and ATM interaction for an efficient DNA damage response (#214)

Using Data-driven network biology to understand how to control cell fate (#215)

MicroRNAs fine-tune transcript abundance in a combinatorial manner during Epithelial-Mesenchymal Transition (#216)

Cameron P Bracken

Identifying functional roles for novel cis-regulatory elements predicted to regulate the Runx1 gene. (#218)

FOXO3 LONGEVITY INTERACTOME ON HUMAN CHROMOSOME 6 (#219)

Investigating the 3’ untranslated region of mRNA in order to understand the drivers of metastasis in primary triple negative breast tumours (#220)

Andrew Pattison

Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling (#221)

Visualisation of telomere recombination-directed replication in ALT cancers (#223)

Joshua AM allen

Identifying WDR5 as a new KLF3 partner protein by co-immunoprecipitation coupled with mass spectrometry (#224)

Krüppel-like Factor 3 (KLF3) regulates the expression of the inflammatory modulator Galectin-3 (Lgals3) (#225)

Kate GR Quinlan

Functional genomic identification of new synaptic regulators. (#226)

Long-range transcriptional regulation of erythropoiesis by KLF1 (#227)

Kevin Gillinder

A mutation in zinc finger domain of human KLF1 causes congenital dyserythropoietic anaemia (CDA) via promiscuous DNA binding and ectopic target gene expression (#228)

KLF1 is a pioneer transcription factor for erythroid cells (#229)

Identification of Putative Direct Target Genes of IKZF1 (Ikaros) in Erythropoiesis (#230)

A study into the role of H3.3 Serine 31 phosphorylation in chromatin regulation (#231)

Developing modifiers of the ALT telomere maintenance pathway (#232)

Christopher G Tomlinson

MegaPlex Targeted Amplicon Sequencing for Increased Efficiency on Illumina Systems (#234)

Jafar S. Jabbari

The use of antisense oligonucleotide-mediated exon skipping to treat Spinocerebellar ataxia type 3 (#235)

Functional validation of obesity-associated genes in vivo (#236)

Victoria Shenton

Genome analysis of a new isolate reddish Planococcus faecalis (#237)

Pyung Cheon Lee

The Burden of Recurrent and Ancestral Mutations in Families with Hypertrophic Cardiomyopathy (#238)

Samantha Barratt-Ross

Expression of the histone H3.3-K27M mutational driver of paediatric glioblastoma causes dwarfism in mice (#239)

Screening for novel epigenetic modifiers and characterizing their molecular role in gene expression control (#240)

Chamila I Wanigasuriya

Investigating the transcriptional differences between in vivo, subcutaneous and orthotopic models of pancreatic cancer. (#241)

Nathan Harmston

Rescuing CFTR expression of mutation specific polymorphisms in Cystic Fibrosis patients (#242)

Kelly M Martinovich

Glucocorticoid Receptor-mediated repression of Versican during murine lung development (#243)

Spliced synthetic genes as internal controls in RNA-seq experiments (#244)

Simon A Hardwick

Transcriptional landscape of an hPSC system of Huntington’s Disease (#245)

Sarah R Langley

3D Cardiomics: An interactive 3D visualisation of the adult cardiac transcriptome (#246)

Assessing Cancer Gene Fusions Using Targeted Capture Sequencing (#247)

James Blackburn

Amplicon-based Diversity Profiling of The Microbiome (#248)

Rachael McNally

Condensin I Jumpstarts Essential Transcription after Mitosis (#249)

Christian F Nielsen

Role of ATRX in maintaining ribosomal DNA stability and chromatin assembly (#250)

Maheshi Udugama

Identification of structural variants from liquid biopsy ctDNA (#251)

Thomas Whitington

Regulation of H2A.Z localisation during the cell cycle (#252)

Using singular value decomposition to alleviate batch effects in RNA sequencing data (#253)

Alexandra L Garnham

To barcode them all (#254)

Megan A. Schischka

Understanding the function of 5-methylcytosine in mRNA biology (#255)

Ulrike Schumann

Genomic DNA replication stress induces parallel mechanisms that alter centromere and telomere structure to induce mitotic cell death (#256)

V. Pragathi Masamsetti

Enrichment of unamplified DNA and long-read SMRT Sequencing to unlock repeat expansion disorders (#257)

Decoding the heart: Mining of the regulatory genome. (#258)

Mirana Ramialison

Telomere loops regulate activation of the DNA damage response by the chromosome end (#259)

Ronnie Ren Jie Low

Utilising capture-seq to identify noncoding RNAs in the ribosomal RNA gene repeat intergenic spacer as potential drivers of malignancy (#260)

Determining how endogenous genomic DNA replication stress translates to ATR inhibitor sensitivity (#261)

Patrick P Stalder

Identification of regions of accessible chromatin from DNA methylome data (#262)

Yuliya V Karpievitch

Development of a whole genome sequencing based classifier to determine telomere maintenance mechanism in tumours (#263)

Spatio-temporal chromatin dynamics during the DNA damage response (#264)

Tara K Bartolec

Disrupting the Piwi-interacting RNA pathway in the mouse hippocampus enhances the memory of conditioned fear (#265)

Power, false discovery rate, and Winner's Curse in eQTL studies (#266)

A mobile form of TREX-2 like (mTREX-2) complex is involved in the coupling of transcription with mRNA export. (#267)

Alexandra Hackmann

State of the art of single cell transcriptomics. (#268)

Developmental profiling of RNA expression using PATseq identifies alternative polyadenylation as an important mechanism for the development of cerebral cortex neurons during mouse brain development. (#269)

Transcriptomic Toolkit for Analysis of Second Generation Sequencing Data in the Cloud (#270)

The Sperm Small RNA Content of Mice is Altered due to Increased Physical Activity (#271)

Shlomo Yeshurun

Investigating the role of the C-terminal binding protein-1 (CTBP-1) in neuronal development and maintenance in Caenorhabditis elegans (#272)

G-quadruplex DNA formation in the genome and its role in fibrosis. (#273)

Priyanka Toshniwal

The interplay between Heterochromatin- Protein 1 (HP1) and H2A.Z in cancer progression (#274)

Dysregulation of rRNA gene chromatin in ovarian cancer (#275)

New Class of Small Molecule Multicarbazole Probes for the Targeting Quadraplex DNA. (#276)

Modelling multi-cellular networks (#278)

The human short-chain dehydrogenase/reductase superfamily and their roles in the regulation of endocrine hormone signalling pathways in cancer. (#280)

Spencer T Greatorex

Construction of developmental lineage relationships in the mammary gland by single-cell RNA profiling (#281)

Searching for the CANVAS disease gene (#282)

Sarah J Beecroft

Chromatin remodelling protein ATRX is involved in resolution of G-quadruplexes across the genome (#283)

A short window of opportunity: DNA polymerase IV is granted limited access to stalled replication forks in Escherichia coli (#284)

The miR-200 family directly regulates mitogen signalling pathways via multiple target genes (#286)

Kaitlin G Scheer

A whole genome CRISPR/Cas9 screen for regulators of JAK-STAT signaling reveals epigenetic control by Setdb1 (#287)

SRSF3 facilitates cell proliferation and controls cell cycle in pluripotent cells through the direct regulation of stem cell specific microRNAs (#289)

Madara Ratnadiwakara

Three-dimensional disorganization of the cancer genome occurs coincident with long-range genetic and epigenetic alterations (#290)

Phillippa Taberlay

Non-consensus binding of runx1 in aml (#291)

Alexandra Woodworth

dRNA-Seq analysis reveals a fascinating transcriptional architecture in Clostridium autoethanogenum (#292)

Renato Lemgruber

Direct competition between DNA binding factors highlights the role of Krüppel-like Factor 1 in the erythroid/megakaryocyte switch (#293)

Gene regulatory networks controlling root developmental plasticity under nitrate and phosphate deficiency in wheat (Triticum aestivum L.) (#294)

Indeewari Dissanayake

Discovering microRNA in complex plant genomes: A comparative bioinformatics analysis of miRNA prediction algorithms in land plants. (#295)

Unravelling the dynamic regulation of transcriptional networks by chromatin and transcription factors (#296)

Jazmine Humphreys

Highly Accurate Genetic Profiling of Circulating Tumor Cells using a Label-free Inertial Microfluidic Approach Coupled with Droplet PCR-based Next-Generation Sequencing (#297)

Size Distribution, Yield, and NGS Library Metrics for cfDNA and cfRNA Extracted from Different Donors, Different Body Fluids, and at Different Time-points (#298)